Bluffmaster! is a comedy crime drama. The movie revolves around a con-man named Roy Kapoor (Abhishek Bachchan). Roy is getting engaged to his girlfriend Simran ‘Simi’ Ahuja (Priyanka Chopra), who is unaware of Roy’s truth. However, on the day of engagement Roy’s truth is revealed and Simi leaves him. Roy is heartbroken and becomes a heavy drinker. One day, he falls unconscious in the middle of the street and is saved by a small-time crook Dittu (Riteish Deshmukh), who begs him to teach him the art of conning. Roy reluctantly agrees and helps him to con. He then learns that he is suffering from a brain tumor and has really less time to live. However, Roy decides to help Dittu one last time to con Chandru (Nana Patekar), a con who duped Dittu’s father and many others of their life savings and Dittu always wanted to take revenge on the man. Will Roy and Dittu succeed in their escapade or Roy’s illness will fail their plan?