Bob Biswas is a crime thriller that revolves around Bob Biswas (Abhishek Bachchan) a hitman-for-hire who has just come out of a coma and finds it hard to recall his criminal past. He tries to reunite with his family including his wife and children but fails to recall the time spent with them as he realizes that he needs money to set his life right. In order to reset everything right, he goes on a killing spree for which he gets paid. How does he deal with his past life and experiences after coming out of the coma, how will he escape the clutches of the police, is he really mentally sick or pretending to be one, all this gets unfolded in the latter part of this psychological thriller?