Jayantabhai Ki Luv Story is a romantic comedy drama that revolves around Simran Desai (Neha Sharma), an engineering graduate, and Jayanta Bhai (Vivek Oberoi), a small-time gangster. Simran travels to Mumbai to pursue a career in the IT sector, however, she faces financial crisis in Mumbai and moves to a low-costing society. Her neighbour, Jayanta Bhai, helps her and the two fall in love with each other. However, the match is disapproved by Simran’s father. What does Jayantabhai do to make his love story a success is what the remaining story is all about.