Madhoshi is a psychological thriller drama. The movie revolves around Anupama Kaul (Bipasha Basu). Anupama is engaged to a man named Arpit (Priyanshu Chatterjee), who leaves for America for a business trip. Meanwhile, Anupama is wooed by a man named Aman (John Abraham), and she falls in love with him. When Arpit returns, Anupama tells him about Aman and wants to break the engagement. Arpit and their families demand to meet Aman, however, things take a turn when everyone realizes that Aman doesn’t even exist, but Anupama strongly believes in Aman’s existence. Is Anupama hiding something? What might be the secret behind Aman’s existence?