Masti is an adult comedy thriller drama. The movie revolves around three men – Meet (Vivek Oberoi), Prem (Aftab Shivdasani), and Amar (Ritesh Deshmukh). The three live a carefree life until they get married. Meet marries Anchal (Amrita Rao), an over-possessive wife. Prem marries Geeta (Tara), who is overly religious, which makes their sex life suffer. Amar marries Bindiya (Genelia D’Souza), an overly-dominant lady. They become unsatisfied and bitter husbands, who are fed up with their married lives. Bored of their regular lives, the three decide to spice up their lives by indulging in an extra-marital affair. The three-start dating and enjoying themselves. However, things take a turn for them, when they become the prime suspects of murder. How the three men prove their innocence and regain the trust of their wives form the climax of the movie.