Om Ka Hari revolves around Hari Sharma (Raghubir Yadav) lives with his family, including his wife (Soni Razdan), two daughters, Vandana and Guddi, and his son, Om Sharma (Anshuman Jha). Om is married to Priya (Ayesha Kapur), and the couple lives separately. During a trip to Kashi, Om begins to understand and follow his father’s advice. However, on the sixth day, Om suddenly falls ill and is admitted to a hospital by Atmaram, where Priya visits him. After recovering, Om returns home with Hari and Priya, bringing the family together once again.