Vadh is a psychological thriller drama. The movie revolves around Dr. Arjun Singh (Nana Patekar), a famous psychiatrist, who lives with his much younger wife Jyoti (Anupama Verma). One night, a serial killer escapes from Arjun’s hospital and his brother, Vijay (Nakul Vaid), a police officer, tries to capture him. After the series of murder of young ladies, Vijay suspects Ariyan (Puru Raaj Kumar), a womaniser, who is also Arjun’s best friend to be the culprit. However, things take a worse turn when Arjun realises that his wife has an extra-marital affair with his best friend. Is Ariyan the serial killer? Will Jyoti be his next target?