Hum Hain Bemisal is an action thriller drama. The movie revolves around Vijay Sinha (Akshay Kumar), an honest police officer. Years ago, Vijay’s father Kishan was murdered by Tuti Shah (Rami Reddy), but Kishan’s friend D’Souza (Pran) was framed for his murder and sent to jail. Vijay starts to hate D’Souza for killing his father and also cuts ties with his friend and D’Souza’s son Michael (Suniel Shetty). Michael grows up and becomes a goon. When D’Souza returns after completing his time in jail, he reveals the truth to Vijay and also tries to find his son Michael. Meanwhile, Tuti Shah makes Michael his target and starts to manipulate him to work for him. Will Vijay be able to punish his father’s real killer? Will D’Souza reunite with his son after so many years?