Mr. X is a science fiction thriller film. The movie revolves around a police officer, Inspector Raghuram ‘Raghu’ Rathod (Emraan Hashmi) who is engaged to Officer Siya Verma (Amyra Dastur). A corrupt police officer plots to murder the Chief Minister and he blackmails Raghu to kill the CM. After killing the CM, Raghu is taken to a rundown factory and left to die. However, he consumes an untested healing solution, which causes him to become invisible. He then sets out to take revenge on all those who landed him in that situation.