My Wife’s Murder is a thriller drama. The movie revolves around Ravi Patwardhan (Anil Kapoor), a young man whose wife goes missing. Sheela (Suchitra Krishnamoorthy), Ravi’s wife, leaves her place to go to Shirdi with her parents but doesn’t arrive at her parent’s place at all. After 24 hours of her departure, Ravi and his father-in-law file a missing report of Sheela. Things take a turn when Sheela’s dead body is found. Ravi becomes the prime suspect of the murder. However, Ravi maintains his innocence. The police don’t find any apparent motive for any unknown person to kill Sheela and suspect Ravi to be the murderer. Will Ravi be able to prove his innocence or end up in jail?