NH10 is a thriller drama that marks the production debut of actress Anushka Sharma. The movie revolves around a married couple, Meera (Anushka Sharma) and Arjun (Neil Bhoopalam), who live in Gurgaon. The two decide to go on a road trip a day prior to Meera’s birthday. While on the road trip, they witness an honour killing of a young couple performed by the bride's brother Satbir (Darshan Kumar), who is a powerful gangster. However, they end up in big trouble when they try to stop the killing. Meera tries to take the help of the police but to no avail and that is the time she decides to take up the mantle on her own and settle scores with Satbir and his men.