Stree 2 is the sequel to the horror comedy thriller Stree (2018), where the people of Chanderi this time face yet another curse by asking 'O Stree Raksha Karna' instead of 'O Stree Kal Aana'. The locals find that a headless entity mysteriously abducts women. Once again, it's up to Vicky (Rajkummar Rao) and his friends Jana (Abhishek Banerjee), Bittu (Aparshakti Khurana), and Rudra (Pankaj Tripathi), who take the help of the unknown girl (Shraddha Kapoor) carrying a ponytail which helps her fight the beheaded evil spirit to save their town and loved ones.