Tumko Meri Kasam is a biopic drama inspired by the life of Dr. Ajay Murdia, the founder of Indira IVF, a nationwide chain of fertility clinics. The story navigates the challenges of how Dr. Ajay Murdia (Ishwak Singh) builds a medical empire while introducing IVF in conservative regions where infertility was solely blamed on women, and how he broke social stigmas. It also delves into his professional struggles and personal life that he shared with his wife and finally how he faces legal trials in court to overcome the challenges that life throws at him.