Yun Hota Toh Kya Hota is a thriller drama. The movie revolves around four different characters, who came from different parts of India and traveled to the US. Tilottama Das-Punj (Konkona Sen Sharma) is married to a man named Hemant (Jimmy Sheirgill), who moves to the US for a job. Tilottama also boards the flight to the USA to reunite with her husband. Salim Rajabali (Irrfan Khan) is involved in a murder case and flees to the US to save himself. Rahul Bhide (Ankur Khanna), a brilliant but poor boy, gets an offer to study at a US-based University and is financially helped by his friend to board the flight. Payal (Shabana Goswami), the daughter of a US-based event organizer boards a flight to join her father abroad. Things take a turn when their flight is hijacked which leads to unfortunate and horrifying situations.