Pratibandh is an action crime drama that follows the story of a young orphaned man named Siddhanth (Chiranjeevi), who grows under the care of a strict school-master. Siddhanth grows up into a detached and short-tempered policeman, as he never received love and care from anyone. As a police officer, Siddhant becomes a cruel, but honest officer who gets in trouble with Spot Nana (Rami Reddy), and refuses to be in favor of him at any cost.