Dhoom Dhaam is an action comedy thriller that follows the story of newlyweds Koyal Chaddha (Yami Gautam) and Veer Poddar (Pratik Gandhi) who are a mismatch from an arranged marriage. On their wedding night as they are about to get acquainted with one another a gang of goons knock at their door asking for 'Charlie'. An encounter with the goons leads the newlyweds into a chaotic chase, dodging goons and cops in a frenzied hunt for a case of mistaken identity.