Jaani Dost is an action revenge drama. The movie revolves around a young man named Veeru (Jeetendra), the son of wealthy tycoon, Raja Dharam Singh, who is a multi-millionaire and owner of a huge property. However, Veeru’s life takes a turn, when an evil man named Cobra (Kader Khan) kills his father to get hold of all his wealth, and later goes after Veeru. Veeru somehow manages to escape Cobra, and later decides to set scores right with Cobra and avenge his father’s death. Helping Veeru in his mission is Raju (Dharmendra) who is a truck driver and an old friend. Will Veeru and Raju succeed in their mission?