Muqaddar Ka Sikandar is a romantic drama where Sikandar (Amitabh Bachchan), an orphan who was given shelter by a rich girl Kaamna (Raakhee Gulzar) in his childhood, falls in love with her but cannot express his emotions as he had worked at their house to make a living. As time passes, Sikandar becomes the messiah of the poor and turns into a successful businessman, his friend Vishal (Vinod Khanna) who works at Kaamna’s father’s office falls in love with the latter. On knowing that Vishal and Kaamna love each other Sikandar sacrifices his love.